Pramlintide Acetate CAS: 196078-30-5 Raw material supply
Product Description
Pramlintide (Symlin) is a relatively new injectable drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary of AstraZeneca )Pramlintide is sold as an acetate salt.
Pramlintide is an analogue of amylin ,a small peptide hormone that is released into the bloodstream by the β-cells of the pancreas along with insulin, after a meal.Like insulin, amylin is completely absent in individuals with Type I diabetes.
Reduction in glycated hemoglobin and weight loss have been shown in insulin-treated patients with type 2 diabetes taking pramlintide as an adjunctive therapy.
By augmenting endogenous amylin, pramlintide aids in the cellular absorption and regulation of blood glucose by slowing gastric emptying, promoting satiety via hypothalamic receptors (different receptors than for GLP-1), and inhibiting inappropriate secretion of glucagon, a catabolic hormone that opposes the effects of insulin and amylin. Pramlintide also has effects in raising the acute first-phase insulin response threshold following a meal.
Company profile
SaiWanTe (Shanghai) New Material Technology Co.,Ltd is a foreign trading company, specializing in developing and producing Organic intermediate . It has its own factory, which procures itself a competitive edge in market. For many years, our company has won many clients' support and trust because it always strives to make high-quality merchandise with favorable price. It commits itself to satisfy every clients, in return, our customer show great confidence and respect for our company. In spite of so many loyal customers won these years, Weitai keeps modest all the time and strives to better itself from every aspect. We are looking forward to cooperating with you and having a win-win relationship with you. Please rest assured that we will satisfy you. Just feel free to contact me.
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